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Biology Assessment Test Items 2001 Movies, Animations and Interactive Tutorial Links Genetic Science Learning Center Key Tutorials -Recent discoveries in the field of epigenetics -- the study of heritable changes in gene function that occur without a change in the DNA sequence -- have blurred the neat picture of mutation and recombination, and are changing the way researchers think about heredity. - Epigenetic mechanisms such as DNA methylation, histone acetylation, and RNA interference, and their effects in gene activation and inactivation, are increasingly understood to be more than "bit players" in phenotype transmission and development. Epigenetics II -Changes to DNA and its associated proteins can alter gene expression without altering the DNA sequence. -Chemical
modifications to the DNA or the histones alter the structure
of the chromatin without changing the nucleotide sequence of
the DNA. Such modifications are described as epigenetic.
1. CDs on presentation system 2 Power Point Presentations with lecture 3. Video Presentations 4. Replication-Transcription-Translation Worksheets 6. Cell Biology Animation-Johnny Kyrk 7. Kimball's Pages a. Chromosomes 6. Animations Replication of DNA(1). Replication Animation #2(1) Transcription Animation #2 7. Gene Maps a. Karyotyping Activity 8. Preliminary Findings of the Human Genome Project 5. Genome Biology 9. Introns a. Introns and Exons 10. The Rules of Protein Structure 12. Jurassic Park Genetics a. Jurassic Park Study Guide |
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Complete
your journey into genetics by extending your knowledge of
DNA Structure and Function. Examine the final animations by
clicking the Organization of Genetic Information link
below.
On April 25, 1953, James Watson and Francis Crick published their Nobel Prize winning description of the DNA double helix, which spawned over the next 50 years unimaginable medical advances including vaccines, diagnostics, drugs, and the complete sequencing of the human genome. -April 2003 will be a pivotal month in the past, present, and future of genetic medicine: -50th anniversary of the discovery of DNA's double helical structure -Completion of the sequencing of the human genome -Preview of the exhibit "Genome: The Secret to How Life Works" at the Smithsonian Institution's Arts and Industries Building. The exhibit is made possible by Pfizer and produced by Clear Channel Exhibitions in collaboration with the National Human Genome Research Institute, National Institutes of Health, Department of Health and Human Services and the Whitehead Institute/MIT Center for Genome Research. The full exhibit opens June 8, 2003 and will run through January 4, 2004. Critical Genetics Project The Critical Genetics Project is based on the precept that there is a crucial problem in molecular genetics, the science that now dominates biomedical research, and in its applications to agriculture, medicine and the production of pharmaceutical drugs. The science was created nearly 50 years ago with the aim of explaining inheritance on the theory that this property, which is unique to living things, is governed by genetic information that originates exclusively in a molecular agent: DNA. Molecular genetics is now confronted with a growing disjunction between this widely accepted premise and an array of discordant experimental results that contradict it. But this disparity is largely unacknowledged, a situation that has engendered applications that irretrievably alter inheritance by transferring isolated segments of DNA or entire genomes into cells in which they do not naturally occur: transgenic microorganisms, animals and plants; in humans, gene therapy, and proposed germ-line modifications as well as cloning. Human Genetics-Do you have the dominant trait? Let's ask a lot of people all over the world which traits they have. One way for students to learn how their physical characteristics, or traits, are inherited is by gathering a great deal of information about specific, easily-seen human features. Students can analyze this information to determine which traits are controlled by dominant genes and how often such dominant genes occur. During this project, students will complete surveys, formulate hypotheses, and use the data compiled by students around the globe to test their hypotheses. BIOCOACH ACTIVITIES From Gene to Protein: Transcription |
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1. Method #1-DNA Extraction from Cheek Cells (Squamous Epithelium) 2. Method #2-DNA Extraction from Cheek Cells (Squamous Epithelium) 3. DNA Extraction-E.coli Demonstration 4. Sickle Cell Anemia: A Case Approach to Teaching High School Genetics Sickle cell anemia is an example of a genetic disease that can serve as a vehicle for teaching many biology concepts. Using a case study approach, opportunities arise to make connections not only to various aspects of genetics and molecular biology, but to physiology, evolution and societal and ethical issues as well. Over the last four decades, essentially since the advent of protein and later nucleic acid sequencing, a number of approaches to derive phylogenetic inference from aligned sequence data have been developed. The parallel development of computers has permitted phylogenetic analyses of longer sequences and larger collections of sequences. |
Movies, Animations and Interactive Tutorial Links 1. Biohealth Links of Cancer Internet Resources 2. Use these resources to interact with the subject matter on genetics to enhance your understanding of how DNA functions. Molecular Links-Demonstrations, Animations and Virtual Books 3. DNA Tutorial |
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Human Genome Reference Links |
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2. Resource Center Primary Database 3. The Human Genome Organization 5. UK Human Genome Project Resource Center 7. Biotech Bio/Chem Resources for Education 8. Genemap 99 |