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Key Tutorials Biology Assessment Test Items 2001 Movies, Animations and Interactive Tutorial Links Genetic Science Learning Center
Epigenetics I -Recent discoveries in the field of epigenetics -- the study of heritable changes in gene function that occur without a change in the DNA sequence -- have blurred the neat picture of mutation and recombination, and are changing the way researchers think about heredity. - Epigenetic mechanisms such as DNA methylation, histone acetylation, and RNA interference, and their effects in gene activation and inactivation, are increasingly understood to be more than "bit players" in phenotype transmission and development. -Changes to DNA and its associated proteins can alter gene expression without altering the DNA sequence. -Chemical
modifications to the DNA or the histones alter the structure
of the chromatin without changing the nucleotide sequence of
the DNA. Such modifications are described as
epigenetic.
1. CDs on presentation system 2 Power Point Presentations with lecture 3. Video Presentations 4. Replication-Transcription-Translation Worksheets 6. Cell Biology Animation - Johnny Kyrk 7. Kimball's Pages a. Chromosomes (1). The Replication Fork d. Transcription 8. Animations Replication of DNA(1). Replication Animation #2(1) Transcription Animation #2 7. Gene Maps a. Karyotyping Activity 8. Preliminary Findings of the Human Genome Project 5. Genome Biology 9. Introns a. Introns and Exons 10. The Rules of Protein Structure 12. Jurassic Park Genetics a. Beyond Jurassic Park:Real Science with Ancient DNA |
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2. The Cold Spring Harbor site will complete your journey into genetics by carrying you into the application of your knowledge of DNA Structure and Function. 
On April 25, 1953, James Watson and Francis Crick published their Nobel Prize winning description of the DNA double helix, which spawned over the next 50 years unimaginable medical advances including vaccines, diagnostics, drugs, and the complete sequencing of the human genome. -April 2003 was a pivotal month in the past, present, and future of genetic medicine: -50th anniversary of the discovery of DNA's double helical structure -Completion of the sequencing of the human genome BIOCOACH ACTIVITIES From Gene to Protein: Transcription From Gene to Protein: Translation (Protein
Cold Spring Harbor - The Dolan Learning Center
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1. Method #1-DNA Extraction from Cheek Cells (Squamous Epithelium) 2. DNA Extraction-E.coli Demonstration 3. 4. Sickle Cell Anemia: A Case Approach to Teaching High School Genetics Sickle cell anemia is an example of a genetic disease that can serve as a vehicle for teaching many biology concepts. Using a case study approach, opportunities arise to make connections not only to various aspects of genetics and molecular biology, but to physiology, evolution and societal and ethical issues as well. Over the last four decades, essentially since the advent of protein and later nucleic acid sequencing, a number of approaches to derive phylogenetic inference from aligned sequence data have been developed. The parallel development of computers has permitted phylogenetic analyses of longer sequences and larger collections of sequences. |
Movies, Animations and Interactive Tutorial Links Genetic Science Learning Center Cracking the Code of Life-PBS Activities and Streaming Video |
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Human Genome Reference Links |
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2. Resource Center Primary Database 3. The Human Genome Organization 5. UK Human Genome Project Resource Center 7. Biotech Bio/Chem Resources for Education 8. Genemap 99 |
